St. Jude found 156 potential targets for chimeric antigen receptor (CAR) T--cell immunotherapy. Explore the discovery's promise to improve cancer therapies.

Scientists have discovered how glioblastoma evades the immune system by inducing pro-tumor macrophages via a glucose based epigenetic modification.

New research examines how the bacteria Escherichia coli, or E. coli -- responsible for most UTIs -- is able to use host nutrients to reproduce at an extraordinarily rapid pace during infection despite the near sterile environment of fresh urine.

Blood vessels in the lungs aren't like the others in the body. This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death. The underlying reasons for this organ-specific vessel stiffening remained a mystery until researchers made a surprising...

The placenta's response to infections from malaria, toxoplasmosis and listeria has been mapped in high resolution, possibly paving the way for new treatment options.

Researchers have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of certain diseases.